Gap junction channels are sites of cytoplasmic communication between contacting cells.In vertebrates, they consist of protein subunits denoted connexins (Cxs) which are encoded by a gene family.According to their Cx composition, gap junction channels show different gating and permeability properties that define which ions and small molecules permea
Abstract Background The optimal antithrombotic strategy early after aortic valve replacement surgery with a biological valve remains controversial due to lack of high-quality evidence.Either oral anticoagulants or acetylsalicylic acid should be considered for the first 3 months.Hypo-attenuated leaflet thickening on cardiac computed tomography has b
Target localization is an important research field in wireless sensor networks and the received signal strength (RSS)-based method is of particular interest.Since traditional Skate Socks RSS-based method is invalid for simultaneously localizing multiple targets, the compressive sensing theory has been applied to develop an effective localization fr
Immunotherapies are revolutionizing cancer care, producing durable responses Mobile Phones and potentially cures in a subset of patients.However, response rates are low for most tumors, grade 3/4 toxicities are not uncommon, and our current understanding of tumor immunobiology is incomplete.While hundreds of immunomodulatory proteins in the tumor m
Adaptation to coastal flood risk is hampered by high uncertainty in the rate and magnitude of sea-level rise.Subsequently, adaptation decisions carry strong risks of under- or over-investment, and could lead to costly retrofitting or unnecessary high Mobile Phones margins.To better allocate resources timely and effectively, and achieve long-term su